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SDMA can be an early indicator of kidney disease and can support the identification of loss of kidney function that can occur secondary to other disease processes.1–4 The 5-minute guide to SDMA addresses the most common questions about SDMA so you can get valuable new insights with your regular chemistry protocols.

  • Who are some key patients that can benefit from SDMA testing?

  • What should I do with an increased SDMA result?

  • When should I include SDMA testing?

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References

  1. Hall JA, Yerramilli M, Obare E, Yerramilli M, Jewell DE. Comparison of serum concentrations of symmetric dimethylarginine and creatinine as kidney function biomarkers in cats with chronic kidney disease. J Vet Intern Med. 2014;28(6):1676–1683. doi:10.1111/jvim.12445
  2. Yerramilli M, Yerramilli M, Obare E, et al. Symmetric dimethylarginine (SDMA) increases earlier than serum creatinine in dogs with chronic kidney disease (CKD) [ACVIM Abstract NU42]. J Vet Intern Med. 2014;28(3):1084–1085. doi:10.1111/jvim.12361
  3. Troìa R, Mascalzoni G, Calipa S, Magagnoli I, Dondi F, Giunti M. Multiorgan dysfunction syndrome in feline sepsis: prevalence and prognostic implication. J Feline Med Surg. 2019;21(6):559–565. doi:10.1177/1098612X18792106
  4. Kenney EM, Rozanski EA, Rush JE, et al. Association between outcome and organ system dysfunction in dogs with sepsis: 114 cases (2003–2007). JAVMA. 2010;236(1):83–87. doi:10.2460/javma.236.1.83

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